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CK14 Polyclonal Antibody

SKU:
CAB24481
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
€129 - €359
Frequently bought together:

Description

CK14 Polyclonal Antibody (CAB24481)

The CK14 Polyclonal Antibody is a crucial tool for researchers studying CK14, a type I keratin expressed in stratified epithelia. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for use in various immunohistochemistry and immunofluorescence applications. By targeting the CK14 protein, researchers can accurately detect and analyze CK14 expression in different cell types, aiding in studies related to epithelial biology, cancer research, and stem cell characterization.CK14 is a key biomarker in identifying and studying different types of epithelial cells, helping researchers understand the role of these cells in tissue development and maintenance.

By using the CK14 Polyclonal Antibody, researchers can gain valuable insights into the functions and characteristics of CK14-positive cells in various physiological and pathological contexts. This antibody is an essential tool for advancing research in areas such as wound healing, skin biology, and cancer progression, providing important data for further discoveries and therapeutic developments.

Product Name:CK14 Polyclonal Antibody
Product Code:CAB24481
Reactivity:Human
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:1000-1:5000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Positive Samples:A431
Cellular Location:Cytoplasm, Nucleus

This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11.

Immunogen:A synthetic peptide corresponding to a sequence within amino acids 372-472 of human CK14 (NP_000517.3).
Sequence:QIQEM IGSVE EQLAQ LRCEM EQQNQ EYKIL LDVKT RLEQE IATYR RLLEG EDAHL SSSQF SSGSQ SSRDV TSSSR QIRTK VMDVH DGKVV STHEQ VLRTK N
Synonyms:KRT14, CK14, EBS3, EBS4, K14, NFJ, keratin 14
Calculated MW:51kDa
Observed MW:Refer to figures

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