The CIZ1 Polyclonal Antibody (CAB17349) is a valuable tool for researchers studying CIZ1, a nuclear matrix protein involved in cell cycle regulation and DNA replication. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human CIZ1 protein, making it suitable for use in Western blotting and immunohistochemistry applications.CIZ1 has been implicated in various cellular processes, including chromatin remodeling and transcriptional regulation, making it a key player in cell proliferation and differentiation. Dysregulation of CIZ1 expression has been linked to cancer development and progression, highlighting its potential as a biomarker or therapeutic target in oncology research.
By utilizing the CIZ1 Polyclonal Antibody, researchers can detect and analyze CIZ1 protein expression in different cell types and tissues, providing valuable insights into its function and potential role in disease pathology. With its versatility and reliability, this antibody is an essential tool for advancing our understanding of CIZ1 biology and its implications in various fields of research.
Product Name:
CIZ1 Rabbit Polyclonal Antibody
SKU:
CAB17349
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 250-440 of human CIZ1 (NP_001124490).
The protein encoded by this gene is a zinc finger DNA binding protein that interacts with CIP1, part of a complex with cyclin E. The encoded protein may regulate the cellular localization of CIP1. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
25792
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse testis, using CIZ1 Rabbit pAb (CAB17349) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
