The CITED2 Polyclonal Antibody is a versatile tool for researchers studying the CITED2 protein, which is involved in various cellular processes such as gene transcription and signal transduction. This antibody, produced in rabbits, has a high affinity for human samples and is suitable for use in Western blot experiments. By binding specifically to the CITED2 protein, the antibody allows for accurate detection and analysis in a range of cell types, making it an essential component for studies in molecular biology and cancer research.CITED2, or Cbp/p300-interacting transactivator 2, plays a crucial role in mediating the expression of genes involved in cell proliferation, differentiation, and development.
Its importance in regulating cellular functions makes it a key target for research on diseases such as cancer, cardiovascular disorders, and developmental abnormalities. By understanding the function of the CITED2 protein, researchers can uncover potential therapeutic targets for treating a variety of human diseases.In conclusion, the CITED2 Polyclonal Antibody offers reliable and specific detection of the CITED2 protein, making it an indispensable tool for researchers exploring the molecular mechanisms underlying various physiological and pathological processes.
Product Name:
CITED2 Polyclonal Antibody
SKU:
CAB24662
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CITED2(NP_001161860.1).
Sequence:
MADH MMAM NHGR FPDG TNGL HHHP AHRM GMGQ FPSP HHHQ QQQP QHAF NALM GEHI HYGA GNMN ATSG IRHA MGPG TVNG GHPP SALA PAAR FNNS QFMG
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:1000 - 1:5000
Synonyms:
ASD8; MRG1; VSD2; MRG-1; P35SRJ; CITED2
Positive Sample:
Rat testis
Conjugate:
Unconjugated
Cellular Localization:
Nucleus.
Calculated MW:
28kDa
Observed MW:
28kDa
The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
10370
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat testis, using CITED2 Rabbit pAb (CAB24662) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
