The CITED2 Polyclonal Antibody (CAB12831) is a valuable tool for researchers studying the CITED2 protein, which plays a critical role in transcriptional regulation and cellular responses to stress. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting CITED2 in human samples, making it ideal for use in Western blotting applications. By binding to the CITED2 protein, this antibody enables accurate detection and analysis of CITED2 expression in a variety of cell types.CITED2 is known for its involvement in various cellular processes, including development, metabolism, and response to environmental stimuli.
Its dysregulation has been implicated in diseases such as cancer, cardiovascular disorders, and developmental abnormalities. Researchers studying CITED2 can gain valuable insights into the molecular mechanisms underlying these conditions and potentially identify new therapeutic targets for intervention.Overall, the CITED2 Polyclonal Antibody (CAB12831) is a reliable tool for investigating the functions and regulatory mechanisms of the CITED2 protein in a research setting. Its specificity, sensitivity, and versatility make it a valuable asset for studies in molecular biology, developmental biology, and disease pathology.
Product Name:
CITED2 Rabbit Polyclonal Antibody
SKU:
CAB12831
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-275 of human CITED2 (NP_001161861.2).
The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
10370
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CITED2 Rabbit pAb (CAB12831) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 10s.
