The CIT Polyclonal Antibody (CAB3668) is a valuable tool for researchers studying CIT, a key protein involved in cellular communication and signaling pathways. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the CIT protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component for studies in cell biology and signaling research.
CIT, also known as CITron, is a multi-functional protein that plays a crucial role in regulating cell proliferation, migration, and cytoskeletal organization. Its importance in cellular processes makes it a promising target for research in areas such as cancer, neurobiology, and developmental biology. Investigating the function of CIT can provide valuable insights into its potential therapeutic applications in diseases involving abnormal cell growth and migration.
Product Name:
CIT Rabbit Polyclonal Antibody
SKU:
CAB3668
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1000-1300 of human CIT (NP_001193928.1).
This gene encodes a serine/threonine-protein kinase that functions in cell division. Together with the kinesin KIF14, this protein localizes to the central spindle and midbody, and functions to promote efficient cytokinesis. This protein is involved in central nervous system development. Polymorphisms in this gene are associated with bipolar disorder and risk for schizophrenia. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
11113
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CIT Rabbit pAb (CAB3668) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.