The CISD2 Polyclonal Antibody (CAB5231) is a valuable tool for researchers studying CISD2, a protein involved in mitochondrial function and iron homeostasis. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the CISD2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in mitochondrial biology, iron metabolism, and cellular signaling pathways.CISD2, also known as CDGSH iron sulfur domain 2, plays a crucial role in regulating mitochondrial function and redox balance.
Dysregulation of CISD2 has been linked to various diseases, including neurodegenerative disorders, metabolic disorders, and cancer. Understanding the function and regulation of CISD2 is essential for developing targeted therapies and treatments for these conditions.Overall, the CISD2 Polyclonal Antibody (CAB5231) is a valuable tool for researchers looking to explore the role of CISD2 in cellular physiology and disease processes. Its high specificity and reactivity make it a reliable choice for studies in mitochondrial biology, iron metabolism, and related fields.
Product Name:
CISD2 Rabbit Polyclonal Antibody
SKU:
CAB5231
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 61-135 of human CISD2 (NP_001008389.1).
The protein encoded by this gene is a zinc finger protein that localizes to the endoplasmic reticulum. The encoded protein binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause of Wolfram syndrome 2.
Purification Method:
Affinity purification
Gene ID:
493856
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CISD2 antibody (CAB5231) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
