The CIRBP Polyclonal Antibody (CAB6559) is a valuable tool for researchers studying Cold-Inducible RNA-Binding Protein (CIRBP), a key player in cellular responses to cold stress and other environmental challenges. This antibody, raised in rabbits, is highly specific to human samples and is validated for use in various research applications, including Western blotting.CIRBP, a stress-responsive protein, is known to play a critical role in regulating cellular processes such as RNA stabilization, gene expression, and cell survival under stressful conditions. Its involvement in processes related to inflammation, cell cycle regulation, and apoptosis makes it a target of interest in studies focused on cancer, neurological disorders, and metabolic diseases.
By detecting and analyzing CIRBP in different cell types, researchers can gain valuable insights into the mechanisms by which this protein functions and its potential implications in various disease contexts. The CIRBP Polyclonal Antibody provides a reliable tool for investigating the role of CIRBP in cellular stress responses and its potential as a therapeutic target in disease interventions.
Product Name:
[KO Validated] CIRBP Rabbit Polyclonal Antibody
SKU:
CAB6559
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human CIRBP (NP_001271.1).
Enables mRNA 3'-UTR binding activity and small ribosomal subunit rRNA binding activity. Involved in mRNA stabilization; positive regulation of translation; and response to UV. Located in cytoplasm and nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
1153
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using [KO Validated] CIRBP Rabbit pAb (CAB6559) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
