The Cinp Polyclonal Antibody (CAB10006) is a vital tool for researchers studying Cinp, a key player in immune regulation and response inhibition. This antibody, derived from rabbit hosts, exhibits high reactivity with human samples and is specifically validated for Western blot applications. By binding to the Cinp protein, this antibody enables precise detection and analysis in various cell types, making it an essential component for investigations in immunology and cancer research.Cinp, also referred to as an immune inhibitory receptor, plays a pivotal role in maintaining immune balance by controlling inflammation and suppressing allergic responses.
Its involvement in immune response modulation positions it as a promising target for research on diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Comprehensive understanding of Cinp's function is fundamental in developing therapeutic interventions that manipulate or enhance immune responses in these disease contexts.
Product Name:
CINP Polyclonal Antibody
SKU:
CAB21188
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human CINP (NP_116019.1).
The protein encoded by this gene is reported to be a component of the DNA replication complex as well as a genome-maintenance protein. It may interact with proteins important for replication initiation and has been shown to bind chromatin at the G1 phase of the cell cycle and dissociate from chromatin with replication initiation. It may also serve to regulate checkpoint signaling as part of the DNA damage response. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
51550
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CINP Rabbit pAb antibody (CAB21188) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
