CIDEA Rabbit Polyclonal Antibody (CAB7655)
- SKU:
- CAB7655
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | CIDEA Rabbit Polyclonal Antibody |
SKU: | CAB7655 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-219 of human CIDEA (NP_001270.1). |
Sequence: | SQTK RVLF TPLM HPAR PFRV SNHD RSSR RGVM ASSL QELI SKTL DALV IATG LVTL VLEE DGTV VDTE EFFQ TLGD NTHF MILE KGQK WMPG SQHV PTCS PPKR SGIA RVTF DLYR LNPK DFIG CLNV KATM YEMY SVSY DIRC TGLK GLLR SLLR FLSY SAQV TGQF LIYL GTYM LRVL DDKE ERPS LRSQ AKGR FTCG |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | CIDE-A; CIDEA |
Positive Sample: | Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Lipid droplet, Nucleus. |
Calculated MW: | 25kDa |
Observed MW: | 25kDa |
This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.
Purification Method: | Affinity purification |
Gene ID: | 1149 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |