The CIDEA Polyclonal Antibody (CAB7655) is a valuable tool for researchers studying CIDEA, a protein involved in lipid metabolism and energy balance. This antibody, generated in rabbits, shows high specificity and sensitivity in detecting CIDEA in human samples, particularly in Western blot applications.CIDEA, known as cell death-inducing DFFA-like effector A, plays a crucial role in regulating lipid storage and energy expenditure in cells. By targeting CIDEA, researchers can investigate its function in metabolic disorders such as obesity, diabetes, and fatty liver disease.
Understanding the molecular mechanisms of CIDEA can provide insights into potential therapeutic targets for these conditions.The CIDEA Polyclonal Antibody enables precise detection and analysis of CIDEA expression in various cell types, making it a versatile tool for studies in metabolic research. Its reliable performance and specificity make it a valuable asset for researchers aiming to elucidate the role of CIDEA in metabolic pathways and related diseases.
Product Name:
CIDEA Rabbit Polyclonal Antibody
SKU:
CAB7655
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-219 of human CIDEA (NP_001270.1).
This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.
Purification Method:
Affinity purification
Gene ID:
1149
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of Mouse heart, using CIDEA Rabbit pAb (CAB7655) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
