The CIB3 Polyclonal Antibody (PAC021933) is a high-quality antibody designed for research involving CIB3, a calcium-binding protein that plays a crucial role in various cellular processes. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications.CIB3 is known to be involved in calcium signaling and has been implicated in various physiological functions, including cell migration, adhesion, and gene expression. By targeting the CIB3 protein, researchers can gain valuable insights into the mechanisms underlying these processes and their potential implications in diseases such as cancer, cardiovascular disorders, and neurological conditions.
With its high reactivity and specificity, the CIB3 Polyclonal Antibody is a valuable tool for studying the function and regulation of CIB3 in different cell types and biological contexts. Its utility in Western blot analysis makes it an essential component for researchers interested in unraveling the complexities of cellular signaling pathways and their role in health and disease.
Antibody Name:
CIB3 Antibody (PACO21933)
Antibody SKU:
PACO21933
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from C-terminal of human CIB3.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Clonality:
Polyclonal
Conjugate:
Non-conjugated
Western blot analysis of extracts from K562 cells, using CIB3 antibody.
Synonyms:
Calcium and integrin-binding family member 3; Kinase-interacting protein 3; KIP 3; CIB3; KIP3
UniProt Protein Function:
CIB3: Interacts with ITGA2B (via C-terminus cytoplasmic tail region); the interaction is stabilized/increased in a calcium and magnesium-dependent mannerProtein type: Calcium-bindingChromosomal Location of Human Ortholog: 19p13.12Molecular Function: calcium ion binding; magnesium ion binding; protein binding
UniProt Protein Details:
NCBI Summary:
This gene product shares a high degree of sequence similarity with DNA-dependent protein kinase catalytic subunit-interacting protein 2 in human and mouse, and like them may bind the catalytic subunit of DNA-dependent protein kinases. The exact function of this gene is not known. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
