The CIB3 Polyclonal Antibody (PACO02438) is a valuable tool for researchers studying the CIB3 protein, which plays a crucial role in cellular processes such as calcium signaling and cell adhesion. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.CIB3, also known as calcium and integrin binding family member 3, is involved in intracellular signaling pathways that regulate cell proliferation, migration, and differentiation. By targeting the CIB3 protein, researchers can gain insights into its function in various cell types and its potential role in diseases such as cancer and cardiovascular disorders.
With its high specificity and reliability in Western blot analysis, the CIB3 Polyclonal Antibody is an essential tool for studies in cell biology, molecular biology, and disease research. By detecting and analyzing the expression of CIB3, researchers can further understand its involvement in cellular processes and potentially identify new therapeutic targets for various medical conditions.
Antibody Name:
CIB3 Antibody
Antibody SKU:
PACO02438
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human, Mouse
Immunogen:
synthesized peptide derived from the C-terminal region of human CIB3.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
CIB3; KIP3; Calcium and integrin-binding family member 3; Kinase-interacting protein 3; KIP 3
UniProt Protein Function:
CIB3: Interacts with ITGA2B (via C-terminus cytoplasmic tail region); the interaction is stabilized/increased in a calcium and magnesium-dependent mannerProtein type: Calcium-bindingChromosomal Location of Human Ortholog: 19p13.12Molecular Function: calcium ion binding; magnesium ion binding; protein binding
UniProt Protein Details:
NCBI Summary:
This gene product shares a high degree of sequence similarity with DNA-dependent protein kinase catalytic subunit-interacting protein 2 in human and mouse, and like them may bind the catalytic subunit of DNA-dependent protein kinases. The exact function of this gene is not known. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
