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CIB1 Monoclonal Antibody [P1D1AT] (CPAB0136)

SKU:
CPAB0136
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
P1D1AT
Applications:
WB
ELISA
€149

Description

system_update_alt Datasheet

CIB1 Monoclonal Antibody [P1D1AT] (CPAB0136)

The CIB1 Polyclonal Antibody (CPAB0136) is a valuable tool for researchers studying CIB1, a calcium and integrin-binding protein involved in cell migration, adhesion, and signaling pathways. This antibody, produced in rabbits, shows high specificity and sensitivity for human samples, making it suitable for Western blot applications. By targeting the CIB1 protein, researchers can effectively study its function in various cellular processes, particularly in the context of cancer metastasis and cell motility.CIB1 is known to interact with integrins and other signaling molecules to regulate cell adhesion and migration, playing a pivotal role in tumor progression and metastasis.

The dysregulation of CIB1 expression has been linked to various types of cancer, making it a promising target for therapeutic interventions aimed at inhibiting cancer cell invasion and metastatic spread. By characterizing the role of CIB1 in cancer biology, researchers can uncover new insights into the mechanisms driving tumor progression and potentially identify novel therapeutic targets for anti-cancer strategies.

Product Name:CIB1 Antibody
Product Sku:CPAB0136
Size:5μg
Host Species:Mouse
Immunogen:Anti-human CIB1 mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CIB1 amino acids 1-191 purified from Ecoli.
Clone:P1D1AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:CIB1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2b
Background:CIB1 (Calcium and integrin binding 1) is regulatory protein with 50% homology to calmodulin and calcineurin B, that encodes a member of the calcium-binding protein family. CIB1 interacts with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining. Also CIB1 is widely expressed and binds to a number of effectors, such as integrin αIIb, PAK1, and polo-like kinases, in different tissues.
Synonyms:Calcium and integrin-binding protein 1, Calmyrin, DNA-PKcs-interacting protein, Kinase-interacting protein, SNK-interacting protein 2-28, SIP2-28, CIB1, CIB, KIP, PRKDCIP.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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