The CIAP1 Polyclonal Antibody (ABX00006) is a valuable tool for researchers studying CIAP1, a key regulator of apoptosis and cell survival pathways. This antibody is raised in rabbits and is highly specific for CIAP1, allowing for accurate detection and analysis in various biological samples. With its validated use in Western blot applications, this antibody is essential for investigations into the role of CIAP1 in cancer, cell death, and inflammation.CIAP1, also known as cellular inhibitor of apoptosis protein 1, is a critical player in controlling cell death processes by inhibiting apoptosis pathways. Dysregulation of CIAP1 is linked to various diseases, including cancer and neurodegenerative disorders, making it a promising target for therapeutic interventions.
By studying CIAP1 expression and function, researchers can gain insights into potential treatment strategies for these conditions.Overall, the CIAP1 Polyclonal Antibody provides researchers with a reliable tool for investigating the complex mechanisms involving CIAP1 and its impact on cellular processes and disease development. Its specificity and sensitivity make it an essential component for any research focused on understanding the role of CIAP1 in health and disease.
Product Name:
cIAP1 Polyclonal Antibody
SKU:
CAB21458
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 331-420 of human cIAP1 (NP_001157.1).
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
329
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using cIAP1 Rabbit pAb (CAB21458) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
