CIAO1 Monoclonal Antibody [PAT6C9A] (CPAB0585)
- SKU:
- CPAB0585
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- PAT6C9A
- Applications:
- WB
- ELISA
Description
CIAO1 Monoclonal Antibody [PAT6C9A] (CPAB0585)
The CIAO1 Polyclonal Antibody (CPAB0585) is a valuable tool for researchers studying CIAO1, a protein involved in cellular processes related to cell proliferation, migration, and invasion. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. By binding to CIAO1, researchers can detect and analyze the protein in a variety of cell types, making it an ideal choice for studies in cancer biology and cell signaling pathways.CIAO1, also known as Cytosolic iron-sulfur protein assembly protein 1, plays a crucial role in maintaining iron-sulfur cluster biogenesis and mitochondrial function.
Dysregulation of CIAO1 has been associated with various diseases, including cancer and neurodegenerative disorders, making it a promising therapeutic target for drug development. Investigating the function and regulation of CIAO1 is essential for advancing our understanding of these diseases and developing targeted therapies to address them.
Product Name: | CIAO1 Antibody |
Product Sku: | CPAB0585 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human CIAO1 mAb, clone PAT6C9A, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CIAO1 protein 1-339 amino acids purified from Ecoli. |
Clone: | PAT6C9A. |
Reactivity: | Other bodies |
Applications: | Western Blot, ELISA |
Purification Method: | CIAO1 antibody was purified by protein-A affinity chromatography. |
Isotype: | IgG1 |
Background: | CIAO1 is a vital component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. CIAO1 protein is required for the maturation of extra mitochondrial Fe/S proteins and seems to specifically modulate the trans-activation activity of WT1. CIAO1 participates in chromosome segregation as a part of the mitotic spindle-associated MMXD complex. |
Synonyms: | CIA1, WDR39, Probable cytosolic iron-sulfur protein assembly protein CIAO1, WD repeat-containing protein 39, CIAO1. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |