The Chuk Polyclonal Antibody (CAB2062) is a key tool for researchers studying the Chuk protein, a critical component in the NF-kB signaling pathway. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards Chuk in human samples, making it an ideal choice for Western blotting applications. By targeting the Chuk protein, researchers can gain insight into its function and role in various cellular processes, particularly in the regulation of immune responses and inflammation.Chuk, also known as IKK-alpha, is a key regulator of NF-kB signaling, a pathway involved in immune and inflammatory responses.
Dysregulation of this pathway has been implicated in various diseases, including cancer, autoimmune disorders, and inflammatory conditions. By studying Chuk using this antibody, researchers can uncover potential therapeutic targets for modulating NF-kB activity and developing treatments for these diseases.Overall, the Chuk Polyclonal Antibody (CAB2062) is a valuable tool for researchers interested in unraveling the complex role of Chuk in immune regulation and disease pathogenesis. Its specificity and reliability make it an essential reagent for studies in immunology, cancer research, and beyond.
Product Name:
IKKα Rabbit Polyclonal Antibody
SKU:
CAB2062
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 600-700 of human IKKα (NP_001269.3).
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.
Purification Method:
Affinity purification
Gene ID:
1147
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using IKKα Rabbit pAb (CAB2062) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
