The CHUK Polyclonal Antibody (CAB0423) is a valuable tool for researchers studying the CHUK protein, a vital component in the NF-κB signaling pathway. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the CHUK protein, researchers can effectively detect and analyze its expression in various cell types, making it an excellent choice for studies in immunology and cancer research.CHUK, also known as IKKα, plays a crucial role in regulating the immune response and promoting cell survival. Dysregulation of the NF-κB pathway, in which CHUK is a key player, has been linked to various diseases, including cancer, inflammatory disorders, and autoimmune diseases.
By understanding the function of CHUK, researchers can gain insights into potential therapeutic targets for these conditions and develop novel treatment strategies.Overall, the CHUK Polyclonal Antibody (CAB0423) offers researchers a reliable tool for investigating the role of CHUK in immune signaling pathways and its potential implications in disease pathology. Its high reactivity and specificity make it a valuable asset for advancing research in the fields of immunology and oncology.
Product Name:
IKKα Rabbit Polyclonal Antibody
SKU:
CAB0423
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 600-700 of human IKKα (NP_001269.3).
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.
Purification Method:
Affinity purification
Gene ID:
1147
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using IKKα antibody (CAB0423).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
