The CHST2 Polyclonal Antibody (CAB15755) is a valuable tool for researchers studying CHST2, a key enzyme involved in chondroitin sulfate biosynthesis. This antibody, developed using rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the CHST2 protein, this antibody enables accurate detection and analysis of CHST2 in various cell types, making it an essential component for studies in glycobiology, cartilage development, and related fields.
CHST2 is crucial for the biosynthesis of chondroitin sulfate, a major component of the extracellular matrix and a key regulator of cell signaling, adhesion, and tissue development. Dysregulation of CHST2 has been implicated in various diseases, including cancer, osteoarthritis, and neurological disorders. By understanding the function and regulation of CHST2, researchers can uncover potential therapeutic targets and pathways for these conditions, paving the way for the development of novel treatments and interventions.
Product Name:
CHST2 Rabbit Polyclonal Antibody
SKU:
CAB15755
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 231-530 of human CHST2 (NP_004258.2).
Golgi apparatus, Single-pass type II membrane protein, trans-Golgi network membrane.
Calculated MW:
58kDa
Observed MW:
60kDa
This locus encodes a sulfotransferase protein. The encoded enzyme catalyzes the sulfation of a nonreducing N-acetylglucosamine residue, and may play a role in biosynthesis of 6-sulfosialyl Lewis X antigen.
Purification Method:
Affinity purification
Gene ID:
9435
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from U-251MG cells, using CHST2 Rabbit pAb (CAB15755) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
