CHRNE Rabbit Polyclonal Antibody (CAB10057)
- SKU:
- CAB10057
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | CHRNE Rabbit Polyclonal Antibody |
SKU: | CAB10057 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-239 of human CHRNE (NP_000071.1). |
Sequence: | KNEE LRLY HHLF NNYD PGSR PVRE PEDT VTIS LKVT LTNL ISLN EKEE TLTT SVWI GIDW QDYR LNYS KDDF GGIE TLRV PSEL VWLP EIVL ENNI DGQF GVAY DANV LVYE GGSV TWLP PAIY RSVC AVEV TYFP FDWQ NCSL IFRS QTYN AEEV EFTF AVDN DGKT INKI DIDT EAYT ENGE WAID FCPG VIRR HHGG ATDG PGET DVIY SLII RRK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:4000 |
Synonyms: | MGI; FIM1; FIMG; ACHRE; CMS1D; CMS1E; CMS2A; CMS4A; CMS4B; CMS4C; FCCMS; FIMG1; SCCMS; CMS1A1; CHRNE |
Positive Sample: | HepG2,Mouse skeletal muscle,Rat kidney,Rat skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse. |
Calculated MW: | 55kDa |
Observed MW: | 45kDa |
Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome.
Purification Method: | Affinity purification |
Gene ID: | 1145 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |