CHRND Rabbit Polyclonal Antibody (CAB10467)
- SKU:
- CAB10467
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | CHRND Rabbit Polyclonal Antibody |
SKU: | CAB10467 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-245 of human CHRND (NP_000742.1). |
Sequence: | LNEE ERLI RHLF QEKG YNKE LRPV AHKE ESVD VALA LTLS NLIS LKEV EETL TTNV WIEH GWTD NRLK WNAE EFGN ISVL RLPP DMVW LPEI VLEN NNDG SFQI SYSC NVLV YHYG FVYW LPPA IFRS SCPI SVTY FPFD WQNC SLKF SSLK YTAK EITL SLKQ DAKE NRTY PVEW IIID PEGF TENG EWEI VHRP ARVN VDPR APLD SPSR QDIT FYLI IRRK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ACHRD; CMS2A; CMS3A; CMS3B; CMS3C; FCCMS; SCCMS; CHRND |
Positive Sample: | A-431,293T,HeLa,Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse. |
Calculated MW: | 59kDa |
Observed MW: | 59kDa |
The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1144 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |