The CHRNB2 Polyclonal Antibody (CAB9808) is a valuable tool for researchers studying the CHRNB2 protein, a subunit of the nicotinic acetylcholine receptor. This antibody, produced using rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the CHRNB2 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for studies in neuroscience, pharmacology, and drug development.
The CHRNB2 protein is involved in neurotransmission and has been implicated in various neurological disorders, including nicotine addiction, epilepsy, and schizophrenia. Understanding the function and regulation of CHRNB2 is crucial for developing targeted treatments for these conditions. By utilizing the CHRNB2 Polyclonal Antibody, researchers can gain valuable insights into the role of this protein in neuronal signaling and potentially discover new therapeutic strategies for neurological diseases.
Product Name:
CHRNB2 Rabbit Polyclonal Antibody
SKU:
CAB9808
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 340-430 of human CHRNB2 (NP_000739.1).
Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy.
Purification Method:
Affinity purification
Gene ID:
1141
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CHRNB2 antibody (CAB9808) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
