CHRNA3 Rabbit Polyclonal Antibody (CAB1674)
- SKU:
- CAB1674
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | CHRNA3 Rabbit Polyclonal Antibody |
SKU: | CAB1674 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 32-240 of human CHRNA3 (NP_000734.2). |
Sequence: | SEAE HRLF ERLF EDYN EIIR PVAN VSDP VIIH FEVS MSQL VKVD EVNQ IMET NLWL KQIW NDYK LKWN PSDY GGAE FMRV PAQK IWKP DIVL YNNA VGDF QVDD KTKA LLKY TGEV TWIP PAIF KSSC KIDV TYFP FDYQ NCTM KFGS WSYD KAKI DLVL IGSS MNLK DYWE SGEW AIIK APGY KHDI KYNC CEEI YPDI TYSL YIRR L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | LNCR2; PAOD2; BAIPRCK; NACHRA3; CHRNA3 |
Positive Sample: | SH-SY5Y,HepG2,Mouse brain,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse. |
Calculated MW: | 57kDa |
Observed MW: | 57kDa |
This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.
Purification Method: | Affinity purification |
Gene ID: | 1136 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |