The CHRNA10 Polyclonal Antibody (CAB3042) is a valuable tool for researchers studying the CHRNA10 protein, a member of the nicotinic acetylcholine receptor family. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. It binds to the CHRNA10 protein, allowing for precise detection and analysis in a variety of cell types.CHRNA10 is known for its role in mediating neurotransmission in the central and peripheral nervous systems. Dysregulation of CHRNA10 has been linked to various neurological disorders such as Alzheimer's disease, Parkinson's disease, and nicotine addiction.
By studying the function of CHRNA10, researchers can gain insights into the underlying mechanisms of these conditions and potentially identify new therapeutic targets.Overall, the CHRNA10 Polyclonal Antibody is a reliable tool for investigating the biology of CHRNA10 in both health and disease. Its high specificity and sensitivity make it ideal for use in neuroscience and pharmacology research projects aimed at understanding the complex roles of nicotinic acetylcholine receptors in various physiological processes.
Product Name:
CHRNA10 Rabbit Polyclonal Antibody
SKU:
CAB3042
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 25-240 of human CHRNA10 (NP_065135.2).
Predicted to enable acetylcholine-gated cation-selective channel activity. Acts upstream of or within positive regulation of cytosolic calcium ion concentration. Predicted to be located in membrane. Predicted to be active in cholinergic synapse and neuron projection. Predicted to be integral component of postsynaptic specialization membrane.
Purification Method:
Affinity purification
Gene ID:
57053
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CHRNA10 antibody (CAB3042) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
