The CHRNA1 Polyclonal Antibody (CAB5306) is a valuable tool for researchers studying the CHRNA1 protein, a subunit of the nicotinic acetylcholine receptor. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the CHRNA1 protein, this antibody enables the detection and analysis of CHRNA1 in various cell types, making it ideal for studies in neuroscience, neurobiology, and pharmacology.The CHRNA1 protein is essential for the function of nicotinic acetylcholine receptors, which play a critical role in neurotransmission and synaptic signaling.
Dysregulation of CHRNA1 has been linked to a variety of neurological disorders, including Alzheimer's disease, Parkinson's disease, and epilepsy. As such, the CHRNA1 Polyclonal Antibody is a valuable tool for researchers seeking to better understand the role of CHRNA1 in these conditions and develop targeted therapies for neurological disorders.
Product Name:
CHRNA1 Rabbit Polyclonal Antibody
SKU:
CAB5306
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 105-220 of human CHRNA1 (NP_000070.1).
The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha subunits and 1 each of the beta, gamma, and delta subunits. This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method:
Affinity purification
Gene ID:
1134
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CHRNA1 Rabbit pAb (CAB5306) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
