The CHRM5 Polyclonal Antibody (CAB5367) is a valuable tool for researchers studying the CHRM5 protein, a member of the muscarinic acetylcholine receptor family known for its involvement in various physiological processes, including neurotransmission and smooth muscle contraction. This antibody, generated in rabbits, exhibits high specificity and reactivity towards human samples, making it suitable for use in Western blot applications.By binding to the CHRM5 protein, this antibody enables accurate detection and analysis in a wide range of cell types, making it an essential tool for studies in neuroscience, pharmacology, and drug development.
The CHRM5 receptor is a target of interest in understanding conditions such as Alzheimer's disease, schizophrenia, and gastrointestinal disorders, making this antibody a valuable asset for researchers seeking to elucidate the role of CHRM5 in health and disease.
Product Name:
CHRM5 Rabbit Polyclonal Antibody
SKU:
CAB5367
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 275-370 of human CHRM5 (NP_036257.1).
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, stimulation of this receptor is known to increase cyclic AMP levels.
Purification Method:
Affinity purification
Gene ID:
1133
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of Mouse spinal cord, using CHRM5 antibody (CAB5367) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
