The CHRm3 Polyclonal Antibody (CAB1602) is a valuable tool for researchers studying CHRm3, a chromodomain helicase DNA-binding protein essential for chromatin remodeling and gene expression regulation. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot analysis. It specifically binds to the CHRm3 protein, allowing for accurate detection and characterization in various cell types.CHRm3 is a key player in chromatin dynamics, influencing gene transcription and cell differentiation processes.
As such, understanding the function and regulation of CHRm3 is crucial for unraveling its role in development, disease, and epigenetic modifications. The CHRm3 Polyclonal Antibody serves as a reliable tool for investigating the mechanisms underlying chromatin remodeling and gene expression, making it a valuable asset for studies in molecular biology, developmental biology, and cancer research.
Product Name:
CHRM3 Rabbit Polyclonal Antibody
SKU:
CAB1602
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 390-475 of human CHRM3 (NP_000731.1).
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities.
Purification Method:
Affinity purification
Gene ID:
1131
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of SH-SY5Y, using CHRM3 antibody (CAB1602) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
