Muscarinic AChR M2 (ACM2) Rabbit Polyclonal Antibody (CAB1567)
- SKU:
- CAB1567
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Muscarinic AChR M2 (ACM2) Rabbit Polyclonal Antibody |
SKU: | CAB1567 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 208-388 of human Muscarinic AChR M2 (ACM2) (NP_001006629.1). |
Sequence: | HISR ASKS RIKK DKKE PVAN QDPV SPSL VQGR IVKP NNNN MPSS DDGL EHNK IQNG KAPR DPVT ENCV QGEE KESS NDST SVSA VASN MRDD EITQ DENT VSTS LGHS KDEN SKQT CIRI GTKT PKSD SCTP TNTT VEVV GSSG QNGD EKQN IVAR KIVK MTKQ PAKK KPPP SREK KVTR T |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | HM2; Muscarinic AChR M2 (ACM2) |
Positive Sample: | SH-SY5Y,HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse. |
Calculated MW: | 52kDa |
Observed MW: | 52kDa |
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1129 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |