CHRM1 Rabbit Polyclonal Antibody (CAB16819)
- SKU:
- CAB16819
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CHRM1 Rabbit Polyclonal Antibody |
SKU: | CAB16819 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CHRM1 (NP_000729.2). |
Sequence: | MNTS APPA VSPN ITVL APGK GPWQ VAFI GITT GLLS LATV TGNL LVLI SFKV NTEL KTVN NYFL LSLA CADL IIGT FSMN LYTT YLLM GHWA LGTL ACDL |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 IF/ICC,1:50 - 1:200 |
Synonyms: | M1; HM1; M1R; CHRM1 |
Positive Sample: | Mouse brain,Rat brain |
Cellular Localization: | Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse. |
Calculated MW: | 51kDa |
Observed MW: | 51kDa |
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.
Purification Method: | Affinity purification |
Gene ID: | 1128 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |