The CHPF Antibody (PACO05365) is a high-quality polyclonal antibody designed for research involving CHPF, a protein involved in regulating cell proliferation and differentiation. This antibody is raised in rabbits and has been validated for use in Western blot applications, allowing for the detection and analysis of CHPF protein levels in various cell types.CHPF, also known as chondroitin polymerizing factor, plays a crucial role in the biosynthesis of chondroitin sulfate, a key component of extracellular matrix and cell surface proteoglycans. Dysregulation of CHPF has been implicated in various diseases, including cancer and inflammatory disorders. Therefore, studying the expression and function of CHPF is essential for understanding its role in disease progression and developing targeted therapies.
The CHPF Antibody (PACO05365) is a valuable tool for researchers in the fields of cell biology, cancer biology, and glycobiology. By specifically binding to CHPF, this antibody enables the precise detection and quantification of CHPF protein levels, allowing for in-depth characterization of its functions in normal and disease states. By utilizing this antibody, researchers can gain insights into the molecular mechanisms underlying CHPF-mediated processes and potentially identify novel therapeutic targets for disease intervention.
CHPF: a type II transmembrane protein. May act as a specific activating factor for chondroitin synthase in chondroitin biosynthesis and polymerization. Protein type: Glycan Metabolism - chondroitin sulfate biosynthesis; EC 2.4.1.226; EC 2.4.1.175; Membrane protein, integral; TransferaseChromosomal Location of Human Ortholog: 2q35Cellular Component: Golgi membraneMolecular Function: glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activityBiological Process: chondroitin sulfate biosynthetic process