CHMP2A Rabbit Polyclonal Antibody (CAB10380)
- SKU:
- CAB10380
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | CHMP2A Rabbit Polyclonal Antibody |
SKU: | CAB10380 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-222 of human CHMP2A (NP_055268.1). |
Sequence: | MDLL FGRR KTPE ELLR QNQR ALNR AMRE LDRE RQKL ETQE KKII ADIK KMAK QGQM DAVR IMAK DLVR TRRY VRKF VLMR ANIQ AVSL KIQT LKSN NSMA QAMK GVTK AMGT MNRQ LKLP QIQK IMME FERQ AEIM DMKE EMMN DAID DAMG DEED EEES DAVV SQVL DELG LSLT DELS NLPS TGGS LSVA AGGK KAEA AASA LADA DADL EERL KNLR RD |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | BC2; BC-2; VPS2; CHMP2; VPS2A; CHMP2A |
Positive Sample: | A-431,HepG2,SW480 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasmic side, Late endosome membrane, Peripheral membrane protein. |
Calculated MW: | 25kDa |
Observed MW: | 37kDa |
CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).
Purification Method: | Affinity purification |
Gene ID: | 27243 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |