CHMP1B Rabbit Polyclonal Antibody (CAB8239)
- SKU:
- CAB8239
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | CHMP1B Rabbit Polyclonal Antibody |
SKU: | CAB8239 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human CHMP1B (NP_065145.2). |
Sequence: | MSNM EKHL FNLK FAAK ELSR SAKK CDKE EKAE KAKI KKAI QKGN MEVA RIHA ENAI RQKN QAVN FLRM SARV DAVA ARVQ TAVT MGKV TKSM AGVV KSMD ATLK TMNL EKIS ALMD KFEH QFET LDVQ TQQM EDTM SSTT TLTT PQNQ VDML LQEM ADEA GLDL NMEL PQGQ TGSV GTSV ASAE QDEL SQRL ARLR DQV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | Vps46B; C10orf2; C18orf2; CHMP1.5; Vps46-2; C18-ORF2; hVps46-2; CHMP1B |
Positive Sample: | NCI-H460,MCF7,SKOV3,U-251MG,Mouse liver,Mouse spleen,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Endosome, Late endosome membrane, Peripheral membrane protein, cytosol. |
Calculated MW: | 22kDa |
Observed MW: | 30kDa |
CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).
Purification Method: | Affinity purification |
Gene ID: | 57132 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |