The CHKA Polyclonal Antibody (CAB15040) is a vital tool for researchers studying the CHKA protein, an enzyme involved in the biosynthesis of phosphatidylcholine, a critical component of cell membranes. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications.The CHKA Polyclonal Antibody binds specifically to the CHKA protein, allowing for detection and analysis in a variety of cell types. Its utility in immunology and cancer research makes it indispensable for investigations into the role of CHKA in cell membrane biogenesis and its potential implications for disease pathology.
With its ability to target the CHKA protein, researchers can gain valuable insights into cellular mechanisms and potential therapeutic targets associated with phosphatidylcholine metabolism. Studies using the CHKA Polyclonal Antibody hold promise for advancing our understanding of diseases related to altered lipid metabolism, offering potential avenues for drug development and precision medicine approaches.
Product Name:
CHKA Rabbit Polyclonal Antibody
SKU:
CAB15040
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human CHKA (NP_001268.2).
The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
1119
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CHKA Rabbit pAb (CAB15040) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
