Chicken Leptin Receptor Recombinant Protein (RPPB0733)
- SKU:
- RPPB0733
- Product Type:
- Recombinant Protein
- Species:
- Chicken
Description
| Product Name: | Chicken Leptin Receptor Recombinant Protein |
| Product Code: | RPPB0733 |
| Size: | 20µg |
| Species: | Chicken |
| Target: | Leptin Receptor |
| Synonyms: | OB Protein, Obesity Protein, OBS, Obesity factor, Leptin Receptor. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution at a concentration of 0.4 mg/ml. |
| Formulation: | The protein was filter sterilized and stored at 4�C (0.2 to 0.5 mg/ml) solution of Tris-HCl buffer, pH 9.0 with 150mM NaCl. |
| Stability: | Sterile solutions at 0.5mg/ml or less are stable at 4°C for several months. |
| Purity: | Greater than 99.0% as determined by:(a) Analysis by SEC-HPLC.(b) Analysis by SDS-PAGE. |
| Amino Acid Sequence: | The sequence of the first six N-terminal amino acids was determined and was found to be Ala-Ile-Asp-Val-Asn-IleBiological ActivityBiological Activity is evidenced by high affinity binding of mammalian leptins at 1:1 molar ratio |
Leptin Receptor is a part of the gp130 family of cytokine receptors that stimulate gene transcription by activating cytosolic STAT proteins. Leptin Receptor plays a role in the regulation of fat metabolism and in novel hematopoietic pathway that is obligatory for normal lymphopoiesis. Leptin Receptorparticipates in the regulation of counter-regulatory response to hypoglycemia by inhibiting neurons of the parabrachial nucleus.Leptin Receptoraffectsspecifically on T lymphocyte responses.
Leptin Binding Domain Chicken Recombinant also called Leptin Receptor produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 208 amino acids and having a molecular mass of 24.5 kDa. Chicken Leptin Receptor consists of the cytokine binding domain of leptin receptor amino acids 420-626 of chicken leptin receptor.The Leptin Binding Domain is purified by proprietary chromatographic techniques.
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