The CHERP Polyclonal Antibody (CAB9702) is a valuable tool for research involving the CHERP protein, a key player in chromatin remodeling and gene expression regulation. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the CHERP protein, researchers can detect and analyze its presence in a variety of cell types, making it ideal for studies in epigenetics and gene regulation.
CHERP, also known as chromatin remodeling and histone acetylation regulator protein, is essential for maintaining proper chromatin structure and facilitating transcriptional processes. Dysregulation of CHERP has been implicated in various disease states, including cancer and developmental disorders. Investigating the function of CHERP can provide insight into the molecular mechanisms underlying these conditions and potentially identify new therapeutic targets for treatment.
Product Name:
CHERP Rabbit Polyclonal Antibody
SKU:
CAB9702
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 650-750 of human CHERP (NP_006378.3).
Enables transmembrane transporter binding activity. Involved in positive regulation of calcineurin-NFAT signaling cascade and release of sequestered calcium ion into cytosol. Acts upstream of or within cellular calcium ion homeostasis and negative regulation of cell population proliferation. Located in perinuclear region of cytoplasm.
Purification Method:
Affinity purification
Gene ID:
10523
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CHERP antibody (CAB9702) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
