The CHDH Polyclonal Antibody (CAB16545) is a valuable tool for researchers studying CHDH, a key enzyme involved in the biosynthesis of choline, an essential nutrient for cell membrane integrity and neurotransmitter synthesis. This antibody, derived from rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.CHDH plays a crucial role in maintaining cellular function by catalyzing the conversion of choline to betaine, a process that is essential for lipid metabolism and DNA methylation. Dysregulation of CHDH activity has been implicated in various diseases, including cardiovascular disorders, liver disease, and metabolic syndromes.
By targeting the CHDH protein, this polyclonal antibody allows for the accurate detection and analysis of CHDH expression levels in different cell types, providing valuable insights into the metabolic pathways regulated by this enzyme. Researchers in the fields of biochemistry, metabolism, and molecular biology will find this antibody particularly useful for investigating the role of CHDH in health and disease.
Product Name:
CHDH Rabbit Polyclonal Antibody
SKU:
CAB16545
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 245-594 of human CHDH (NP_060867.2).
The protein encoded by this gene is a choline dehydrogenase that localizes to the mitochondrion. Variations in this gene can affect susceptibility to choline deficiency. A few transcript variants have been found for this gene, but the full-length nature of only one has been characterized to date.
Purification Method:
Affinity purification
Gene ID:
55349
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using CHDH Rabbit pAb (CAB16545) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Negative control (NC):JurkatExposure time: 1s.
