The CHD7 Polyclonal Antibody (CAB17180) is a valuable tool for researchers studying CHD7, a chromatin remodeling protein implicated in various developmental processes. This antibody, raised in rabbits, exhibits high specificity and sensitivity in detecting CHD7 protein levels in human samples, making it ideal for use in Western blot applications.CHD7 plays a crucial role in chromatin remodeling and transcriptional regulation, thereby affecting gene expression patterns that are essential for proper development of various tissues and organs.
Mutations in the CHD7 gene have been associated with developmental disorders such as CHARGE syndrome, highlighting the importance of studying the function of this protein.By using the CHD7 Polyclonal Antibody, researchers can investigate the expression levels and localization of CHD7 in different cell types and tissues, contributing to a better understanding of its role in development and disease. This antibody can aid in identifying potential therapeutic targets and developing treatments for CHD7-related conditions.
Product Name:
CHD7 Rabbit Polyclonal Antibody
SKU:
CAB17180
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CHD7 (NP_060250.2).
This gene encodes a protein that contains several helicase family domains. Mutations in this gene have been found in some patients with the CHARGE syndrome. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
55636
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using CHD7 Rabbit pAb (CAB17180) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5min.
