CHD4 Rabbit Polyclonal Antibody (CAB11574)
- SKU:
- CAB11574
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | CHD4 Rabbit Polyclonal Antibody |
SKU: | CAB11574 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1520-1690 of human CHD4 (NP_001264.2). |
Sequence: | ELAE VEEN KKMS QPGS PSPK TPTP STPG DTQP NTPA PVPP AEDG IKIE ENSL KEEE SIEG EKEV KSTA PETA IECT QAPA PASE DEKV VVEP PEGE EKVE KAEV KERT EEPM ETEP KGAA DVEK VEEK SAID LTPI VVED KEEK KEEE EKKE VMLQ NGET PKDL NDEK QKK |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:100 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | CHD-4; Mi-2b; SIHIWES; Mi2-BETA; CHD4 |
Positive Sample: | HeLa,Jurkat,293T,HT-1080 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center. |
Calculated MW: | 218kDa |
Observed MW: | 280kDa |
The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 1108 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |