The CHD4 Polyclonal Antibody (CAB11574) is a valuable tool for researchers studying CHD4, a key player in chromatin remodeling and gene expression regulation. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards CHD4 protein in human samples, making it an ideal choice for Western blot applications.CHD4, also known as chromodomain helicase DNA-binding protein 4, is involved in various cellular processes such as DNA repair, transcriptional regulation, and chromatin remodeling. Dysregulation of CHD4 has been linked to cancer progression, making it a promising target for cancer research.
By detecting and analyzing CHD4 protein levels in different cell types, researchers can gain insights into its role in gene expression control and cellular functions.Furthermore, understanding the functions of CHD4 can provide valuable information for developing targeted therapies for cancer and other diseases associated with chromatin remodeling. With its reliable performance and specificity, the CHD4 Polyclonal Antibody (CAB11574) is a valuable tool for investigating the role of CHD4 in various biological processes and disease pathways.
Product Name:
CHD4 Rabbit Polyclonal Antibody
SKU:
CAB11574
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1520-1690 of human CHD4 (NP_001264.2).
The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
1108
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CHD4 Rabbit pAb (CAB11574) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
