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CHD4 Monoclonal Antibody

SKU:
CAB23537
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
IHC
€139 - €529
Frequently bought together:

Description

CHD4 Monoclonal Antibody (CAB23537)

The CHD4 Monoclonal Antibody is a key tool for researchers studying the CHD4 protein, which is involved in chromatin remodeling and gene expression regulation. This monoclonal antibody, produced through hybridoma technology, exhibits high specificity and sensitivity in detecting CHD4 in a variety of experimental settings.CHD4, a member of the CHD (chromodomain helicase DNA-binding) family, is known for its role in epigenetic regulation and chromatin organization. Dysregulation of CHD4 has been implicated in various diseases, including cancer and developmental disorders.

By targeting CHD4 with this monoclonal antibody, researchers can gain insights into its function and potential therapeutic implications.Whether studying gene transcription, DNA repair, or stem cell differentiation, the CHD4 Monoclonal Antibody offers reliable performance in techniques such as immunofluorescence, immunoprecipitation, and flow cytometry. With its ability to specifically recognize CHD4 in different cell types and tissues, this antibody is an essential tool for advancing research in molecular biology and biomedical science.

Product Name:CHD4 Monoclonal Antibody
Product Code:CAB23537
Reactivity:Human, Mouse, Rat
Applications:Immunohistochemistry
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC59887
Reactivity:Human, Mouse, Rat
Tested Applications:IHC-P, ELISA
Key Applications:Immunohistochemistry
Recommended Dilution:IHC-P 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Cellular Location:Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center

The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.

Immunogen:Recombinant protein of human CHD4.
Sequence:Email for sequence
Synonyms:CHD-4, Mi-2b, SIHIWES, Mi2-BETA
Calculated MW:218kDa
Observed MW:Refer to figures

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