The CHD2 Polyclonal Antibody (CAB5895) is a valuable tool for studying the CHD2 protein, a key player in chromatin remodeling and gene regulation processes. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blotting applications. By binding specifically to the CHD2 protein, researchers can accurately detect and analyze its expression in a variety of cell types, making it an ideal choice for studies in genetics, epigenetics, and developmental biology.
CHD2 is known to be involved in DNA repair, transcriptional regulation, and maintenance of genomic stability, making it a crucial factor in various cellular processes. Dysregulation of CHD2 expression has been linked to developmental disorders, neurological diseases, and cancer, highlighting its importance in human health and disease. By targeting CHD2 with this specific antibody, researchers can gain valuable insights into its function and potential therapeutic implications in various pathological conditions.
Product Name:
CHD2 Rabbit Polyclonal Antibody
SKU:
CAB5895
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-223 of human CHD2 (NP_001036037.1).
The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
1106
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CHD2 antibody (CAB5895) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
