The CHD2 Polyclonal Antibody (CAB13477) is a valuable tool for researchers studying the CHD2 protein, which is involved in chromatin remodeling and gene regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.The CHD2 protein is a key player in DNA damage repair and transcriptional regulation, making it essential for maintaining genomic stability and controlling gene expression. Dysregulation of CHD2 has been linked to various diseases, including cancer and neurodevelopmental disorders.
With the ability to specifically bind to the CHD2 protein, this polyclonal antibody enables accurate detection and analysis of CHD2 expression in a variety of cell types. Its use in research investigating the role of CHD2 in disease pathogenesis and potential therapeutic targets makes it a valuable tool for studies in molecular biology and genetics. By understanding the functions of CHD2, researchers can uncover new insights into disease mechanisms and develop targeted therapies for improved patient outcomes.
Product Name:
CHD2 Rabbit Polyclonal Antibody
SKU:
CAB13477
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1729-1828 of human CHD2 (NP_001262.3).
The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
1106
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of rat brain, using CHD2 antibody (CAB13477) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
