The CHD1L Polyclonal Antibody (CAB14264) is a key tool for researchers studying the CHD1L protein, which is known for its role in chromatin remodeling and gene regulation. This antibody, generated in rabbits, shows high reactivity specifically with human samples and has been validated for use in Western blot applications. By binding to the CHD1L protein, this antibody allows for the detection and analysis of CHD1L in various cell types, making it an essential component for studies in molecular biology, genetics, and cancer research.CHD1L is a chromatin remodeler that is involved in the regulation of gene expression, DNA repair, and genome stability.
Dysregulation of CHD1L has been implicated in various cancer types, making it a promising target for therapeutic intervention. By understanding the function and activity of CHD1L, researchers can uncover potential new pathways for cancer treatment and drug development.Overall, the CHD1L Polyclonal Antibody (CAB14264) is a valuable tool for researchers looking to delve deeper into the mechanisms of gene regulation and chromatin remodeling, with potential implications for cancer research and therapeutic development.
Product Name:
CHD1L Rabbit Polyclonal Antibody
SKU:
CAB14264
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 320-570 of human CHD1L (NP_001243267.1).
This gene encodes a DNA helicase protein involved in DNA repair. The protein converts ATP to add poly(ADP-ribose) as it regulates chromatin relaxation following DNA damage. Overexpression of this gene has been linked to several types of cancers.
Purification Method:
Affinity purification
Gene ID:
9557
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CHD1L Rabbit pAb (CAB14264) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
