The CHD1 Monoclonal Antibody is a valuable tool for researchers studying CHD1, a chromatin remodeling protein known to play a role in gene regulation and DNA repair. This antibody, produced using hybridoma technology, has high specificity for CHD1 and has been validated for use in various applications such as immunofluorescence and immunohistochemistry.CHD1 is essential for maintaining genome stability and proper gene expression, making it a key player in cellular processes such as cell proliferation and differentiation. Dysregulation of CHD1 has been linked to various diseases, including cancer and developmental disorders.
By using the CHD1 Monoclonal Antibody, researchers can investigate the function and localization of CHD1 in different cell types and tissues, providing valuable insights into its role in health and disease. Overall, the CHD1 Monoclonal Antibody is a reliable tool for researchers interested in studying chromatin remodeling and gene regulation, with the potential to contribute to advancements in fields such as cancer biology, developmental biology, and epigenetics.
Product Name:
CHD1 Monoclonal Antibody
SKU:
CAB23240
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant protein of human CHD1.
Tested Applications:
WBIHC-PELISA
Recommended Dilution:
WB,1:500 - 1:1000 IHC-P,1:50 - 1:200
Synonyms:
CHD-1; PILBOS; CHD1
Positive Sample:
K-562
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm, Nucleus.
Calculated MW:
197kDa
Observed MW:
250kDa
The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template.
Purification Method:
Affinity purification
Gene ID:
1105
Clone Number:
ARC59018
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from K-562 cells, using CHD1 Rabbit mAb (CAB23240) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
