The Chat Polyclonal Antibody (CAB13244) is a valuable tool for researchers studying CD300A, a cell surface molecule known for its role in immune regulation and inhibition of immune responses. Raised in rabbits, this antibody is highly reactive with human samples and has been validated for use in Western blot applications. By specifically binding to the CD300A protein, researchers can easily detect and analyze its expression in various cell types, making it an ideal choice for studies in immunology and cancer research.CD300A, also referred to as an immune inhibitory receptor, plays a crucial role in maintaining immune homeostasis by regulating inflammation and suppressing allergic reactions.
Its involvement in immune response modulation highlights its importance as a target for research on diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of CD300A is essential for developing therapies that can either enhance or modulate immune responses in these disease contexts.Overall, the Chat Polyclonal Antibody (CAB13244) provides researchers with a reliable tool for studying CD300A and its implications in immune regulation and disease pathology.
Product Name:
CHAT Rabbit Polyclonal Antibody
SKU:
CAB13244
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 331-630 of human CHAT (NP_065574.4).
This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.
Purification Method:
Affinity purification
Gene ID:
1103
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using CHAT Rabbit pAb (CAB13244) at 1:2500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
