CHAT Rabbit Polyclonal Antibody (CAB12420)
- SKU:
- CAB12420
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Neuroscience
Frequently bought together:
Description
Product Name: | CHAT Rabbit Polyclonal Antibody |
SKU: | CAB12420 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 331-630 of human CHAT (NP_065574.4). |
Sequence: | TQLR KIVK MASN EDER LPPI GLLT SDGR SEWA EART VLVK DSTN RDSL DMIE RCIC LVCL DAPG GVEL SDTH RALQ LLHG GGYS KNGA NRWY DKSL QFVV GRDG TCGV VCEH SPFD GIVL VQCT EHLL KHVT QSSR KLIR ADSV SELP APRR LRWK CSPE IQGH LASS AEKL QRIV KNLD FIVY KFDN YGKT FIKK QKCS PDAF IQVA LQLA FYRL HRRL VPTY ESAS IRRF QEGR VDNI RSAT PEAL AFVR AVTD HKAA VPAS EKLL LLKD AIRA QTAY TVMA ITGM AIDN HLLA LREL |
Tested Applications: | IHC-P ELISA |
Recommended Dilution: | IHC-P,1:50 - 1:100 |
Synonyms: | CMS6; CMS1A; CMS1A2; CHOACTASE; CHAT |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, neuron projection, nucleus, synapse |
Calculated MW: | 83kDa |
This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.
Purification Method: | Affinity purification |
Gene ID: | 1103 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |