The CHAMP1 Polyclonal Antibody (CAB11690) is a valuable tool for researchers studying the CHAMP1 protein, which is known to play a role in immune regulation and cell division. This antibody, generated in rabbits, is highly specific and reacts strongly with human samples. It has been validated for use in Western blot applications, allowing for the detection and analysis of CHAMP1 in various cell types.CHAMP1, also known as chromosome alignment maintaining phosphoprotein 1, is crucial for proper chromosome segregation during cell division. Dysregulation of CHAMP1 has been implicated in certain types of cancer, making it a promising target for cancer research and drug development.
By utilizing the CHAMP1 Polyclonal Antibody, researchers can further explore the functions and mechanisms of CHAMP1 in both normal and disease states.With its specificity and reliability, the CHAMP1 Polyclonal Antibody (CAB11690) is an essential tool for studies in cell biology, cancer biology, and immunology. Its application in Western blotting ensures accurate and consistent results, allowing researchers to advance their understanding of CHAMP1 and its potential therapeutic implications.
Product Name:
CHAMP1 Rabbit Polyclonal Antibody
SKU:
CAB11690
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 563-812 of human CHAMP1 (NP_115812.1).
This gene encodes a zinc finger protein that functions as a regulator of chromosome segregation in mitosis. The encoded protein is required for correct alignment of chromosomes on the metaphase plate, and plays a role in maintaining the attachment of sister kinetochores to microtubules from opposite spindle poles. Mutations in this gene are associated with an autosomal dominant form of intellectual disability.
Purification Method:
Affinity purification
Gene ID:
283489
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CHAMP1 Rabbit pAb (CAB11690) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
