p60 CAF1 Rabbit Polyclonal Antibody (CAB6259)
- SKU:
- CAB6259
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | p60 CAF1 Rabbit Polyclonal Antibody |
SKU: | CAB6259 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 270-559 of human p60 CAF1 (NP_005432.1). |
Sequence: | SRKN LKRP IAHL PCPG KATL AVRC CPVY FELR PVVE TGVE LMSL PYRL VFAV ASED SVLL YDTQ QSFP FGYV SNIH YHTL SDIS WSSD GAFL AISS TDGY CSFV TFEK DELG IPLK EKPV LNMR TPDT AKKT KSQT HRGS SPGP RPVE GTPA SRTQ DPSS PGTT PPQA RQAP APTV IRDP PSIT PAVK SPLP GPSE EKTL QPSS QNTK AHPS RRVT LNTL QAWS KTTP RRIN LTPL KTDT PPSS VPTS VIST PSTE EIQS ETPG DAQG SPPE LKRP RLDE NKGG TESL DP |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | CAF1; MPP7; CAF-1; CAF1A; CAF1P60; CAF-IP60; MPHOSPH7; p60 CAF1 |
Positive Sample: | HeLa,293T,MCF7,U-251MG |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 61kDa |
Observed MW: | 70kDa |
Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair.
Purification Method: | Affinity purification |
Gene ID: | 8208 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |