CHAC1 Rabbit Polyclonal Antibody (CAB15584)
- SKU:
- CAB15584
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | CHAC1 Rabbit Polyclonal Antibody |
SKU: | CAB15584 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-222 of human CHAC1 (NP_077016.3). |
Sequence: | MKQE SAAP NTPP TSQS PTPS AQFP RNDG DPQA LWIF GYGS LVWR PDFA YSDS RVGF VRGY SRRF WQGD TFHR GSDK MPGR VVTL LEDH EGCT WGVA YQVQ GEQV SKAL KYLN VREA VLGG YDTK EVTF YPQD APDQ PLKA LAYV ATPQ NPGY LGPA PEEA IATQ ILAC RGFS GHNL EYLL RLAD FMQL CGPQ AQDE HLAA IVDA VGTM LPCF CPTE QALA LV |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | CHAC1 |
Positive Sample: | Mouse stomach |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Golgi apparatus, cytosol, trans-Golgi network. |
Calculated MW: | 24kDa |
Observed MW: | 38kDa |
This gene encodes a member of the gamma-glutamylcyclotransferase family of proteins. The encoded protein has been shown to promote neuronal differentiation by deglycination of the Notch receptor, which prevents receptor maturation and inhibits Notch signaling. This protein may also play a role in the unfolded protein response, and in regulation of glutathione levels and oxidative balance in the cell. Elevated expression of this gene may indicate increased risk of cancer recurrence among breast and ovarian cancer patients.
Purification Method: | Affinity purification |
Gene ID: | 79094 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |