CGGBP1 Rabbit Polyclonal Antibody (CAB4231)
- SKU:
- CAB4231
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | CGGBP1 Rabbit Polyclonal Antibody |
SKU: | CAB4231 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-167 of human CGGBP1 (NP_003654.3). |
Sequence: | MERF VVTA PPAR NRSK TALY VTPL DRVT EFGG ELHE DGGK LFCT SCNV VLNH VRKS AISD HLKS KTHT KRKA EFEE QNVR KKQR PLTA SLQC NSTA QTEK VSVI QDFV KMCL EANI PLEK ADHP AVRA FLSR HVKN GGSI PKSD QLRR AYLP DGYE NENQ LLNS QDC |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CGGBP; p20-CGGBP; CGGBP1 |
Positive Sample: | Raji,HeLa,293T,Jurkat |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 19kDa |
Observed MW: | 20kDa |
This gene encodes a CGG repeat-binding protein that primarily localizes to the nucleus. CGG trinucleotide repeats are implicated in many disorders as they often act as transcription- and translation-regulatory elements, can produce hairpin structures which cause DNA replication errors, and form regions prone to chromosomal breakage. CGG repeats are also targets for CpG methylation. In addition to its ability to bind CGG repeats and regulate transcription, this gene is believed to play a role in DNA damage repair and telomere protection. In vitro studies indicate this protein does not bind to methylated CpG sequences.
Purification Method: | Affinity purification |
Gene ID: | 8545 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |