The CGB5 Polyclonal Antibody (CAB6486) is a valuable tool for researchers studying CGB5, a protein that plays a critical role in placental development and pregnancy. This antibody, produced in rabbits, exhibits high reactivity towards human samples and has been validated for use in Western blot applications. By specifically binding to CGB5, it enables accurate detection and analysis in various cell types, making it an ideal choice for studies in reproductive biology and pregnancy-related research.CGB5, also known as chorionic gonadotropin beta 5, is a key player in the maintenance of pregnancy and the regulation of fetal development.
Its expression pattern and function have been linked to various pregnancy-related complications and disorders, making it a promising target for investigating infertility, miscarriages, and gestational disorders. By understanding the mechanisms of CGB5, researchers can uncover new insights into reproductive health and potentially develop therapies for reproductive disorders.
Product Name:
CGB5 Rabbit Polyclonal Antibody
SKU:
CAB6486
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-165 of human CGB5 (NP_000728.1).
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 5 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene.
Purification Method:
Affinity purification
Gene ID:
93659
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CGB5 antibody (CAB6486) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
