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CGB Antibody (PACO02372)

SKU:
PACO02372
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€269
Frequently bought together:

Description

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CGB Antibody (PACO02372)

The CGB Antibody (PACO02372) is a high-quality polyclonal antibody specifically designed for research involving CGB, a crucial protein in pregnancy and reproductive health. This antibody, raised in rabbits, exhibits strong reactivity with human samples and has been validated for use in various applications, including Western blotting. By binding to the CGB protein, this antibody enables accurate detection and analysis in a diverse range of cell types, making it an excellent choice for studies in reproductive biology and infertility research.

CGB, also known as chorionic gonadotropin beta subunit, plays a vital role in early pregnancy by supporting the development of the placenta and maintaining hormonal balance. Its significance in reproductive health makes it a valuable target for investigation into conditions such as infertility, miscarriage, and pregnancy-related disorders. Understanding the function of CGB is essential for developing diagnostic tools and therapeutic interventions that can improve outcomes for individuals facing reproductive challenges.

Antibody Name:CGB Antibody
Antibody SKU:PACO02372
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:Human
Immunogen:synthesized peptide derived from the C-terminal region of human Choriogonadotropin Beta.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:CGB; CGB3; CGB5; CGB7; CGB8; Choriogonadotropin subunit beta; CG-beta; Chorionic gonadotrophin chain beta
UniProt Protein Function:CGB: Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. Belongs to the glycoprotein hormones subunit beta family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Secreted, signal peptide; Inhibitor; Secreted

Chromosomal Location of Human Ortholog: 19q13.32

NCBI Summary:This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 8 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]
UniProt Code:P01233
NCBI GenInfo Identifier:116184
NCBI Gene ID:94115
NCBI Accession:P01233.1
Molecular Weight:22kDa
NCBI Full Name:
NCBI Synonym Full Names:chorionic gonadotropin beta subunit 8
NCBI Official Symbol:CGB8  
NCBI Protein Information:chorionic gonadotropin, beta polypeptide 8
UniProt Protein Name:
Protein Family:Gonadotropin
UniProt Gene Name:

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